✦ Now Accepting New Patients
In-Clinic & Telehealth Available
630-857-9333
387 Shuman Blvd Suite 204E Naperville, Illinois 60563
Home About Services
— Medical Weight Loss — Semaglutide — Tirzepatide
Research Blog Financing Contact Check Your Eligibility
DuPage Medical Wellness
RESEARCH
Evidence-Based Medicine

Clinical Research and
Scientific Studies

Every therapy we offer at DuPage Medical Wellness is supported by peer-reviewed research. This page provides direct links to the key studies underlying our clinical protocols.

Core Weight Loss Therapies

Tirzepatide Clinical Outcomes

Below are the primary outcomes from the pivotal SURMOUNT clinical trials, demonstrating the dual GIP and GLP-1 receptor agonist's efficacy in significant body weight reduction.

New England Journal of Medicine

SURMOUNT-1: Tirzepatide Once Weekly for the Treatment of Obesity

In this 72-week double-blind trial, participants taking the 15mg dose achieved an average of 20.9% body weight reduction compared to only 3.1% in the placebo group. Over 50% of the maximum dose group lost 20% or more of their body weight.

Read Full Study
Nature Medicine

SURMOUNT-4: Continued Weight Loss Trajectory

Demonstrated that withdrawing Tirzepatide after a 36-week lead-in period led to weight regain, while participants who continued treatment maintained weight loss or experienced further reductions, emphasizing the need for chronic management.

Read Full Study
Established Metabolic Protocols

Semaglutide Clinical Outcomes

Data from the monumental STEP trials establishing the GLP-1 receptor agonist as a foundational treatment for chronic weight management and cardiovascular risk reduction.

New England Journal of Medicine

STEP 1: Once-Weekly Semaglutide in Adults with Overweight or Obesity

Over 68 weeks, participants receiving a 2.4 mg subcutaneous dose achieved a mean body weight change of −14.9%, combined with significant improvements in cardiometabolic risk factors compared to lifestyle intervention alone.

Read Full Study
JAMA Network

STEP 4: Effect of Subcutaneous Semaglutide vs Placebo

Participants switching to a placebo after 20 weeks regained significant weight, while those continuing Semaglutide 2.4 mg therapy experienced an additional 7.9% weight loss leading to week 68, proving the efficacy of continuous use.

Read Full Study
The Lancet

SELECT Trial: Cardiovascular Outcomes

Showed a 20% reduction in major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with overweight or obesity and established cardiovascular disease but without diabetes.

Read Full Study

Questions About Our Protocols?

Our physician is happy to discuss the evidence behind any therapy we offer during your consultation.

Book a Consultation
DMW
Start Today

Start your consultation today.

In-clinic in Naperville or via telehealth.

Or call us at 630-857-9333